Eighteen-year-old midfielder Anthony Hartigan has had a successful knee operation, but he has been ruled out for the rest of this season.
The AFC Wimbledon academy product made 16 first-team appearances in 2017/18, before his progress was interrupted by a knee injury.
Speaking during an interview for iFollow, Neil Cox said: "Anthony has had a bit of a sore knee and we had a look at it. The injury needed some work done on it, so we thought the operation would be best for him now. He was able to train for two or three weeks and then had to miss a week, so we thought we'd get it done and he would miss the rest of this season. It's a big shame for us and for the boy, but he'll come back fitter and stronger next year."
There was more positive news to report on Kwesi Appiah, who is recovering well from a hamstring operation.
"Kwesi (Appiah) has been in training this week, which is good to see. He's been in on the bike and he's been brilliant around the boys, giving them credit. It's been a hard season for us, but he's around them, cheering them on and having a bit of banter with them. It's good to see."
All at AFC Wimbledon wish both players all the best in their recuperations.
The full interview with Neil Cox, ahead of Oxford, is now on iFollow.